Cancer: Angiogenesis Inhibition Assay
The zebrafish model is gaining relevance in pre-clinical trials due to its small size, transparency, ease to manipulate and rapid development. This model has a high genetic homology with humans (over 85%) as well as important parallels in organogenesis and functional mechanisms
Biobide has developed a method to detect the capability of a compound to inhibit angiogenesis as part of efficacy pharmacology studies. Angiogenesis, the development of new blood vessels from existing vasculature, is essential in normal diabetic retinopathy, psoriasis and tumor growth and metastasis. Thus, the molecular dissection of angiogenic signaling is clinically relevant.
Services
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EASZY Assay: Estrogen Pathway
Ecotox-Assays / Specific-Toxicity-Assays / -
Zebrafish Sperm Cryopreservation and In Vitro Fertilization
Specific-Toxicity-Assays / -
Zebrafish Models for Amyotrophic Lateral Sclerosis
Specific-Toxicity-Assays / -
Kidney Toxicity
Specific-Toxicity-Assays / -
Sperm quality assessment
Specific-Toxicity-Assays / -
Muscle toxicity
Specific-Toxicity-Assays / -
Acutetox Assay - Ecotox
Ecotox-Assays / -
Daphnia Immobilization
Ecotox-Assays / -
Microplate Alga Growth Inhibition Test
Ecotox-Assays / -
Antioxidation Assay
Efficacy-Assays / -
Regeneration Assay
Efficacy-Assays / -
Melanin Quantification Assay
Efficacy-Assays / -
Thyroid Disruption Assay
Ecotox-Assays / -
Neurodegenerative and Rare Diseases
Efficacy-Assays / Disease-Model-Generation / -
Cancer: Angiogenesis Inhibition Assay
Efficacy-Assays / -
Multitox Assay
Specific-Toxicity-Assays / -
Immunotox Assay
Specific-Toxicity-Assays / -
Ototox Assay
Specific-Toxicity-Assays / -
Neurotox Assay
Specific-Toxicity-Assays / -
Hepatotox Assay
Specific-Toxicity-Assays / -
Cardiotox Assay
Specific-Toxicity-Assays / -
Teratotox Assay
General-Toxicity-Assays / -
Acutetox Assay
General-Toxicity-Assays / -
Disease Model Generation
Disease-Model-Generation / -
Target validation
Target-Validation /