biobide's blog

Polyester is a synthetic polymer highly prized for its strength, resistance to wrinkles or shrinking, and quick-drying properties. Its versatility and cost-effectiveness make it highly popular in the textile industry, and it is used extensively in apparel, home textiles, and various technical applications.

The application of animal models in research has significantly advanced our understanding of complex biological processes and disease mechanisms. Among different animal models, rodents are the most common model in biomedical research. However, alternative models such as Zebrafish lately have been getting greater recognition in developmental biology, especially in the study of developmental stages of vertebrates. 

The Drug Discovery and Development process encompasses several phases, and pre-clinical studies are among the most relevant ones. Pre-clinical studies in Drug Development bridge the gap between in vitro and in silico models to the introduction to human clinical trials. 

The Drug Discovery and Development process is long and goes through several phases, often taking over decades. The process includes different in vitro and in vivo testings that allow to analyze the efficacy and toxicity of potential drug candidates.

Humanity is in a constant battle against diseases, with pharmaceutical and biotechnological companies playing a crucial role in the fight. Research and development (R&D) companies rely on a Contract Research Organization (CRO) to assist in this endeavor. 

What does ex vivo exactly mean? What’s the meaning of in vivo and in vitro? What’s the difference between in vitro and in vivo?

In this blog post, we will explore what does in vitro means, what is in vitro testing and when are in vitro studies preferred to in vivo ones.

Good practices in scientific research and regulatory compliance ensure integrity and reliability in non-clinical studies. These practices, better known as Good Laboratory Practices, a full form of GLP, make clinical health and safety decisions trustworthy and reproducible. They guarantee scientific rigor, the framework upon which the credibility of laboratory findings stands.  

GLP are part of Good Practice (GXP), a collection of quality guidelines and regulations designed to ensure that products are safe, meet their intended use, and adhere to quality processes during manufacturing, control, storage, and distribution.

The unstoppable advance of medicine and the pharmaceutical industry has increased the volume of animal experimentation. Animal testing is crucial in Drug Discovery and Development, bridging in vitro research and human clinical trials.

Living in an industrialized world exposes us to various manufactured products, from personal care items and consumer goods to pesticides. These everyday items may contain chemicals known as  Endocrine-Disrupting Chemicals (EDCs), capable of interfering with the endocrine system's normal functioning in humans and animals.