biobide's blog

Zebrafish, also known as Danio rerio, has captivated researchers and aquarists alike with its vibrant color patterns and genetic tractability. Among vertebrates, Zebrafish exhibit one of the most striking pigment patterns, making them a model organism for studying the genetic and cellular mechanisms underlying Danio fish pigmentation and color changes.

Danio rerio, commonly known as Zebrafish, is widely used as a New Alternative Model (NAM) in scientific research due to their genetic similarities to humans and their ease of maintenance in laboratory settings. 

Danio rerio, commonly known as Zebrafish, is a small freshwater fish that has gained significant prominence as a New Alternative Model (NAM) for in vivo research, rivaling traditional animal models like rodents. This species offers a unique combination of characteristics that make it indispensable for developmental biology, genetics, and beyond.

Animal testing has always played a crucial role in biomedical research and in Drug Discovery and Development, providing important insights that have led to significant medical advancements. Despite the controversies surrounding its ethical implications, animal testing remains the groundwork of every life sciences investigation practice due to the exceptional insights it provides. 

High-Content Screening (HCS) and High-Throughput Screening (HTS) are indispensable methods during the early stages of Drug Discovery and Development for identifying novel compounds with the potential to become effective therapies.

This article delves into the application of Zebrafish as models for human diseases, highlighting their impact on biomedical research. Among various human disease models, Zebrafish has emerged as a powerful and versatile system. It is a valuable model organism for the study of vertebrate biology, being well-suited to both developmental and genetic analysis. 

The Drug Discovery and Development process consists of several sequential steps that aim to ensure a safe and effective profile of a new drug candidate before market approval. 

In particular, in the pre-clinical phase it is crucial to elucidate promising candidates to hopefully reach a clinical trial. The step that allows the passage between these two phases is defined as drug lead optimization, the final phase of the Drug Discovery process.

What is algae and Uses? In this article, we will explain what algae are, providing a rigorous definition of algae and remarking on their multifaceted contributions to ecosystem health and environmental management.

Fluorescent proteins are essential cell and molecular biology reporters. Among these proteins, there is a red fluorescent protein called mCherry which is a remarkable example, especially for its unique properties and applications in molecular and cellular biology as an intracellular probe. 

Polyester is a synthetic polymer highly prized for its strength, resistance to wrinkles or shrinking, and quick-drying properties. Its versatility and cost-effectiveness make it highly popular in the textile industry, and it is used extensively in apparel, home textiles, and various technical applications.