OECD

Chronic toxicity studies are specialized assays designed to evaluate the potential adverse health effects resulting from repeated or continuous exposure to a substance over an extended period. These studies aim to characterize the long-term impact of such exposure on biological systems. 

The Organization for Economic Co-operation and Development (OECD) and the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) both play crucial roles in harmonizing global regulations on chemicals and drugs to ensure their safe use in humans and the environment.